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Questions and Answers from our United States Medical Licensing Examination Updated Study Material are edited by our certified professionals with accuracy for 100% pass guaranteed of USMLE Actual Test. Please check the free demo of United States Medical Licensing Examination Exam Practice Material before purchased.
Updated: Jul 19, 2026
Q & A: 400 Questions and Answers

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.
USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.
USMLE Step 1 is a one-day (8 hours) examination. It includes 322 multiple-choice questions divided into 7 blocks of 46 items (60 minutes are given for completion of each block).
Reference: http://www.usmle.org/step-1/#question-formats
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Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.
| Section | Objectives |
|---|---|
| Topic 1: Cardiovascular System | - Cardiac and Vascular Disorders
|
| Topic 2: Multisystem Processes and Disorders | - Systemic Conditions
|
| Topic 3: Reproductive System | - Male and Female Reproductive Health
|
| Topic 4: Hematopoietic and Lymphoreticular Systems | - Blood and Immune Disorders
|
| Topic 5: Renal and Urinary System | - Kidney and Urinary Disorders
|
| Topic 6: General Principles | - Foundational Medical Sciences
|
| Topic 7: Skin and Related Connective Tissue | - Dermatologic Conditions
|
| Topic 8: Respiratory System | - Pulmonary Medicine
|
| Topic 9: Human Development | - Growth and Development
|
| Topic 10: Gastrointestinal System | - Digestive System Disorders
|
| Topic 11: Musculoskeletal System | - Bones, Joints, and Muscles
|
| Topic 12: Central and Peripheral Nervous Systems | - Neurologic Disorders
|
| Topic 13: Endocrine System | - Hormonal Regulation and Disease
|
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